Published
I really do not know the answer to this, however, I can take a stab at it--perhaps because in pediatrics, the main reason one goes into cardiac arrest has to do with respiratory distress (unless there is unknown cardiac issues). Additionally, peds have a faster and more profound reaction to epi than adults--and atropine given to children can be risky.
An immature nervous system. Also children...babies lack the ability to increase the strength of the contraction to increase cardiac output...they only increase heart rate. So.....to increase perfusion and cardiac output thereby increasing end organ perfusion Epi is used.
http://www.medicine.virginia.edu/clinical/departments/pediatrics/education/pharm-news/2006-2010/201007.pdfIn the face of decreased perfusion, epinephrine is used to produce alpha-adrenergicvasoconstriction which increases systemic vascular resistance. This results in
increased aortic diastolic pressure, improving coronary and cerebral perfusion
Anastasiak
69 Posts
Hi,
I was wondering if anyone knows (the reasoning behind) WHY epinephrine is given for bradycardia in PALS (to pediatric patients) but not in ACLS (for adults)?
For adults, the first drug given in ACLS is atropine...
Thank you