EID Journal: Original Antigenic Sin and Pandemic H1N1

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Here is an interesting discussion on original antigenic sin [OAS], and they even tell you what it means, in case you didn't know, as well as where the term came from. Maybe not light reading for the weekend, but you will learn something about the immune system that most folks don't know about.

In the most recent edition of the EID Journal we get a letter suggesting OAS as an explanation for the age shift to a younger demographic we saw with novel H1N1, along with a separate commentary.

Admittedly these are confusing, often technical discussions, cloaked in more than a little uncertainty. Luckily Robert Roos, Editor of CIDRAP News, has once again stepped up with an excellent summary of this difficult concept to help us along.

No . . . you won't find any definitive answers here, but you will find some intriguing questions.

More at: EID Journal: Original Antigenic Sin And Pandemic H1N1

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