Case Study: Solve A Neurologic Mystery

This is a case study involving an elderly female with complex medical history who presented with altered mental status of unclear etiology. The patient in this case is unable to give a history. Specialties Critical Case Study

Updated:  

There are no reliable sources who witnessed the events leading to patient presentation making it more difficult to ascertain the etiology of her condition. The author hopes to elicit a discussion of her case among peers in critical care nursing.

Background / Social History

RS is a 70-year-old female who lives independently in a first-floor apartment in the city. She has no close relatives but has neighbors who know her very well and check in on her from time to time. She hires a cleaning lady that does her house cleaning and laundry every week. Her nearest relative is a niece who lives in the same state but is 8 hours away by car.

Past History

Her medical history includes anxiety disorder, hypertension, hyperlipidemia, COPD, and mild kidney insufficiency.

She has a 40 pack/year history of smoking.

She has no known allergies.

Medications

  • Paroxetine 20 mg daily
  • Lorazepam 1 mg daily as needed for anxiety
  • Losartan 100 mg daily
  • Amlodipine 10 mg daily
  • Simvastatin 40 mg daily
  • Tiotropium 18 mcg inhaled daily
  • Albuterol MDI 2 puffs 4 times a day as needed

Present History / CC

On the day of her ED admission, her niece had been calling her phone and had been unable to get hold of her. Her niece called a neighbor who stated that she has not seen RS in 3 days. Concerned about RS's condition, the neighbor knocked on her door and heard no response. Luckily she was able to open the door as it was unlocked. Upon entering the living room, the neighbor found RS lying unconscious on the floor. She had frothy secretions from her mouth and had urinated on herself. She immediately called 911. She was intubated at the scene by EMS responders for airway protection due to her altered mental status.

Vital Signs

  • BP 180/100
  • HR 110
  • RR 32
  • T 38.5 C
  • O2sat 88% on RA prior to intubation

Diagnostic Studies

  • In the ED, RS pertinent labs showed a WBC of 15,000 mm3, a lactate of 2.5 mmol/L, and CPK of 20,000 U/L. Neurologic exam was significant for agitation and inability to follow commands with sedation wean. She was hyperreflexic with increased muscle tone. She is moving all her extremities equally and has no abnormal pupillary response. She is sedated on Propofol. CV exam reveals sinus tachycardia with BP of 110/50, her skin is warm to touch. Respiratory exam reveals rhonchi in upper lung fields with moderate white secretions via ET tube
  • ABG: 7.36, 38, 82, 19, -3, 100% on ACVC: 16X400, FiO2 of 0.5 PEEP of 5.
  • CXR reveals mild cardiomegaly, a hyperinflated lung silhouette and mild RLL opacity.
  • Non-contrast CT Scan of her brain showed focal vasogenic edema in the basal ganglia.

The remainder of the exam revealed normal findings.

The ED was particularly busy that evening so RS was immediately transferred out to ICU without further testing in the ED. Because of her complex medical condition, she was transferred to the MICU under your care as her primary RN.

What thoughts run in your head that could possibly explain what caused RS's presentation?

What further testing would you anticipate?

How would you care for RS as her nurse?

For this exercise to be fun and informative, answer in the following manner:

  1. List possible explanations you would expect to hear from her medical team that could explain her neurologic presentation and why.
  2. Tests you would anticipate.
  3. Interventions you would provide as the bedside nurse and why.

Note: This is an actual case and the outcome is already established.

1) first thing that comes to my mind is the patient is post-ictal. The frothy sputum indicates either pulmonary edema but is also very common with seizures. She could and most likely has an aspiration pneumonia secondary to seizure activity. She has skeletal muscle breakdown secondary to being on the ground for undetermined amount of time. With her CPK of 20000 she probably was on the floor quite some time and will most likely have rhabdomyolosis.

2) serial CPK levels every 12 hours, aggressive crystalloid hydration, renal consultation, loading dose of Phenytoin or utilize Keppra, control hypertension, keep patient sedated and allow for brain edema to decrease. Prevent hypertension, prevent acidosis, keep K on upper side of normal, monitor kidney function closely, antibiotics for aspiration pneumonia and begin feeding the patient via tube feeds as soon as possible.

1 Votes
Specializes in Vents, Telemetry, Home Care, Home infusion.

Don't know how I missed this thread when first posted in 2013. Great responses from members listing body system assessment, suggested labs/diagnostic testing and clinical nursing considerations. Learned a new diagnosis today.

2 Votes