Anatomy & Physiology Help

1 Post

Sorry to be posting here, but you all are the ones that can help me! I am stuck on the following case study:

30-year-old female demonstrated a subtle onset of the following symptoms: dull facial expression; droopy eyelids; puffiness of the face and periorbital swelling; sporifice, dry hair; dry, scaly skin; evidence of intellectual impairment; lethargy; a change of personality; bradycardia (60 b/min); a blood pressure of 90/70; anemia (hematocrit 27); enlarged heart (upon radiological exam); constipation, and hypothermia. Plasma concentrations of total and free T3 and T4 were as follows:

T4 T3

total 3.0 ug/dL 0.14 ng/dL

free 0.6 ng/dL 0.01 ng/dL

Radioimmunoassay (RIA) of peripheral blood indicated elevated TSH levels. A TSH stimulation test did not increase the output of thyroid hormones from the thyroid gland.

I cannot figure out this woman's diagnosis! Any information or hints would be appreciated!