I'm starting in January, and while I don't have children yet, I can feel your pain regarding uprooting your family. I first decided I wanted to do this in 2001 as an RT, but my wife had just nailed down a great job that required us to move to Asheville, NC. We gladly moved, as Asheville is one of the few places we truly wanted to live. Once established in her new position, we had to make the decision to either stay in Asheville while I went back for my BSN and then move to wherever I got accepted or to move to where I wanted to go to school, pursue my BSN there, and hope to get in when the time came. We chose the later, and it was a huge step of faith for us. It was a very difficult decision, as we loved Asheville, and my wife was going to move from a great sales territory to a terrible sales territory. It was a very difficult time as the move was expensive, my wife's territory was challenging, we had to carry two mortgages for six month, and my new job was a big pay-cut from Asheville, but we knew that we were making the right decision for the long run. We made the move in 2005, and thinking that if all went well, i'd become a CRNA in July of 2012 seemed like torture at times, but we gradually started realizing that our new town wasn't so bad and that we needed to focus on living and enjoying everyday and not when I'd be through and we could move back to where we wanted to be. That seems like yesterday now, and I know that the next three years are going to fly. We love our new home, love our neighbors, love our town, and are very happy we made the tough decisions with faith that hard work and perseverance would ultimately pay off. There is definitely a large dose of pain for this ultimate gain, but you only live once and you aren't getting any younger. If anesthesia is what you want to do, the trials and tribs you go through to get there will only make the results more gratifying. If you want it, get your spouse and children on board and go for it.