While Villanova is recognized nationally, in my opinion that has more to do with the success of their basketball team than anything academically related. I tend to agree with Tootsie with respect to TJU - it is one certainly one of the most respected health care learning institutions in the country and at least in the medical community, is as well known as 'Nova. There is probably just as good a case to be made that the TJU program is superior to Villanova but in reality, neither is better or worse than the other.
With respect to cost, I strongly advise that you take this into account no matter where you attend. While grads from Villanova and TJU may have an easier time finding nursing jobs
than those from other schools (and even that's debatable) that is relative. While you may read about a "nursing shortage", that is much more myth than fact. The reality is that all new RN's in most parts of the country are finding it difficult to land nursing jobs. If you look at the data, you will find that in many areas, very few new nursing jobs are being created at the same time that thousands of new nurses are entering the job market. This situation is particularly acute in Phila where there a lots of nursing programs
(23 in the city and surrounding counties) who produce lots of new nurses (2,142 new RN's in 2009) who have to compete in a very tight job market (a total of 80 new RN jobs between 2008 and 2009 - the 2010 data is not yet available from the BLS).
This is not meant to discourage you from nursing, only to alert you to the reality of the workplace. I'd ask any school that you're planning to attend what their placement rate for new grads is. I know that you said that job security is not a motivator for you but I strongly suspect that you would not enjoy the stress of desperately searching for nursing job immediately upon graduation because you need to start repaying $50k or more in loans within 6 months.