Does anyone out there have a protocol for Penicillin desentiziation?, We hardly ever do it, but occasionally there are pregnant women with syphillis who need PCN and are so called allergic to it. We usually call pharmacy and get their protocol and use it (which is all about dosage strength) , but what about the specifics for our maternity unit?, what if she has an anaphylactic reaction? our patients are not admitted (they are out patients), no labs, what if they code?(we do it in our recovery room where the crash cart is near), But I just feel unsafe doing PCN desentiziation, and when I voiced this to my director she said why don't you make a protocol? How rude!!!!! :angryfire