united state

loriangel14, RN · Jan 31, 2014

Not all drugs are administered the same way. It totally depends on the drug and how it is ordered.

Esme12, ASN, BSN, RN · Feb 1, 2014

you dilute and administer according to the manufacturers recommendations or the policy at your facility.

narwater · Feb 1, 2014

I mean prophylaxis antibiotic preop. E.x cefazoline or what the common prophylaxis antibiotic preoperative you give and how?

loriangel14, RN · Feb 1, 2014

It would depend on what is ordered.You would prepare according to instructions.

narwater · Feb 4, 2014

The order to give zinacef 1.5 g IV preop. How to give what is your protocol plz give an example don't tell depend

Esme12, ASN, BSN, RN · Feb 4, 2014

I can tell you are NOT in the US. Here in the US our antibiotics are prepared by pharmacy. They come to the floors mixed for each patient individually. IF it needs to be mixed on the floor we follow the manufacturers recommendations.

Our surgeons are very specific about when to administer usually IV secondary/piggyback 1 hour prior to the procedure.

Preparation of Solution and Suspension
The directions for preparing ZINACEF for both IV and IM use are summarized in Table 3.
For Intramuscular Use
Each 750-mg vial of ZINACEF should be constituted with 3.0 mL of Sterile Water for Injection. Shake gently to disperse and withdraw completely the resulting suspension for injection.
For Intravenous Use
Each 750-mg vial should be constituted with 8.3 mL of Sterile Water for Injection. Withdraw completely the resulting solution for injection.
Each 1.5-gram vial should be constituted with 16.0 mL of Sterile Water for Injection, and the solution should be completely withdrawn for injection.
The 7.5-gram pharmacy bulk vial should be constituted with 77 mL of Sterile Water for Injection; each 8 mL of the resulting solution contains 750 mg of cefuroxime.
Each 750-mg and 1.5-gram infusion pack should be constituted with 100 mL of Sterile Water for Injection, 5% Dextrose Injection, 0.9% Sodium Chloride Injection, or any of the solutions listed under the Intravenous portion of the COMPATIBILITY AND STABILITY section.
Table 3. Preparation of Solution and Suspension
[TABLE=class: table_layout]
[TR]
[TD=bgcolor: #e6f1ff, align: center] Strength[/TD]
[TD=bgcolor: #e6f1ff, colspan: 2, align: center] Amount of Diluent to Be Added (mL)[/TD]
[TD=bgcolor: #e6f1ff, align: center] Volume to Be Withdrawn[/TD]
[TD=bgcolor: #e6f1ff, align: center] Approximate Cefuroxime Concentration (mg/mL)[/TD]
[/TR]
[TR]
[TD=colspan: 2, align: left] 750-mg Vial[/TD]
[TD=align: right] 3.0 (IM)[/TD]
[TD=align: center] Total*[/TD]
[TD=align: center] 225[/TD]
[/TR]
[TR]
[TD=colspan: 2, align: left] 750-mg Vial[/TD]
[TD=align: right] 8.3 (IV)[/TD]
[TD=align: center] Total[/TD]
[TD=align: center] 90[/TD]
[/TR]
[TR]
[TD=colspan: 2, align: left] 1.5-gram Vial[/TD]
[TD=align: right] 16.0 (IV)[/TD]
[TD=align: center] Total[/TD]
[TD=align: center] 90[/TD]
[/TR]
[TR]
[TD=colspan: 2, align: left] 750-mg Infusion pack[/TD]
[TD=align: right] 100 (IV)[/TD]
[TD=align: center] —[/TD]
[TD=align: center] 7.5[/TD]
[/TR]
[TR]
[TD=colspan: 2, align: left] 1.5-gram Infusion pack[/TD]
[TD=align: right] 100 (IV)[/TD]
[TD=align: center] —[/TD]
[TD=align: center] 15[/TD]
[/TR]
[TR=class: Last]
[TD=colspan: 2, align: left] 7.5-gram Pharmacy bulk package[/TD]
[TD=align: right] 77 (IV)[/TD]
[TD=align: center] Amount Needed†[/TD]
[TD=align: center] 95[/TD]
[/TR]
[TR=class: First]
[TD=colspan: 5] *Note: ZINACEF is a suspension at IM concentrations.[/TD]
[/TR]
[/TABLE]

http://www.globalrph.com/cefuroxime_dilution.htm