My daughter had a port installed about 3 months ago, which has not been right since the beginning. Blood return happened easily only once...the first access. Since then, she has had to do the dance, or had tpa instilled. Fluoroscope revealed a tiny clot at the top back of the port. Her arm has been swelling terribly with each infusion (yes, port is on the left) and her left hand becomes almost unusable. Both lower extremities are edematous, also, with the right one being the worst. She must spend most of her time lying down, with L arm and bil legs ups on pillows to keep it under control. She has one more infusion, and then the port is coming out. Docs are not happy she is insisting on having it removed, because she still has more chemo -- a lot more --- to get. She's been having Taxol and Herceptin weekly for a total of 12 weeks. Next she will get Herceptin alone weekly, for six weeks, along with daily radiation txs. Then, she will receive Herceptin every 3 weeks, until next May, for a total of a year's tx. I am a retired oncology nurse; have not practiced for five or six years, and, in fact, Herceptin is new to me. But, with all the rounds if chemo I infused via ports, I never had a patient with the kind of swelling my daughter is enduring. Since, the second infusion, when a blood return was difficult - and, because the area was swollen and very sensitive to the touch -- I have felt the port was incorrectly placed. Docs rejected removing and replacing, however, and encouraged her to continue, claiming all is well. And, even now, after she has demanded the port come out after the next infusion, the docs want her to keep that port. I can't imagine her suffering through nine more months with it (she is miserable), yet I find myself walking a fine line here when she asks my advice. She needs to complete the tx. The docs tell her she may not be able to finish the tx without the port, because she has had so much edema in the L arm that a good vein may not be found to continue IVF. They cannot use her right arm as the lymph nodes were removed there. She is asking my advice. I am very concerned about the clot and the edema. Yet, I am also concerned about her having to stop treatment. I am also a breast ca survivor x2. I had chemo and radiation the first time around in 1985, but it was a totally different tx than she is receiving now. Nineteen years later I had a mastectomy, although it was a new and different ca of the same breast. The first time around, I was not an R.N. My survival encouraged me to become an oncology nurse. So, the second time around, I was one and knew a little more. But, now a few years out of practice, I am bewildered....and, it is my daughter.....somehow, this is harder to face than my own cancers. Any thoughts are appreciated.