Juvenile Arthritis or Down's Syndrome and Cancer?

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    If you have a child with juvenile arthritis and Down's syndrome, which one would be more likely to get cancer? I would think that that since juvenile arthritis is an auto-immune disease, it would be more likely to happen in that case than a child with Down's syndrome. This was a discussion in class and some of us feel we were right. I tried finding information on any website, but am not having any luck. Does anyone have a website that would have this info? Thanks.
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  4. 1
    Try searching "risk for cancer Down syndrome" and " ... juvenile arthritis." You might also ask some nurse practitioners who work with these populations for leads. Your opinions aren't worth much without data.
    Esme12 likes this.
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    You also need to consider what meds they are on for treatment and how the incidence os cancer compares to the treatment choices.
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    As a mother of a child with rheum arthritis, I would tend to believe it is the RA child. Many of the meds my son has been on have had a black box warning for lymphomas and other types of cancers. I also think an auto-immune disease like arthritis could increase your risk. But, this is not my clinical area, so it is just a guess.
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    RA children have about a 2-4 times higher chance of getting lymphoma type cancer and Down children have a 20 times higher chance of getting leukemia
  8. 0
    Quote from brithoover
    RA children have about a 2-4 times higher chance of getting lymphoma type cancer and Down children have a 20 times higher chance of getting leukemia

    See what you can find out when you search? Gold star, brithoover.
    Now, OP, what does that mean? Compared to ... ?
  9. 0
    Good work, brithoover!

    References for those?
  10. 1
    I work in peds heme/onc. We study from APHON text: Essentials of Pediatric Hematology/Oncology Nursing
    GrnTea likes this.


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