Juvenile Arthritis or Down's Syndrome and Cancer?

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  1. This is a discussion on Juvenile Arthritis or Down's Syndrome and Cancer? in General Nursing Student, part of Nursing Student ... If you have a child with juvenile arthritis and Down's syndrome, which one would be more likely to...

    by Feb 25
    If you have a child with juvenile arthritis and Down's syndrome, which one would be more likely to get cancer? I would think that that since juvenile arthritis is an auto-immune disease, it would be more likely to happen in that case than a child with Down's syndrome. This was a discussion in class and some of us feel we were right. I tried finding information on any website, but am not having any luck. Does anyone have a website that would have this info? Thanks.
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    by Java Mama Feb 25 4:16 pm
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  3. 7 Comments so far...

  4. Feb 25 by
    Try searching "risk for cancer Down syndrome" and " ... juvenile arthritis." You might also ask some nurse practitioners who work with these populations for leads. Your opinions aren't worth much without data.
    Esme12 likes this.
  5. Asst. Admin
    Feb 25 by
    You also need to consider what meds they are on for treatment and how the incidence os cancer compares to the treatment choices.
  6. Feb 25 by
    As a mother of a child with rheum arthritis, I would tend to believe it is the RA child. Many of the meds my son has been on have had a black box warning for lymphomas and other types of cancers. I also think an auto-immune disease like arthritis could increase your risk. But, this is not my clinical area, so it is just a guess.
  7. Feb 25 by
    RA children have about a 2-4 times higher chance of getting lymphoma type cancer and Down children have a 20 times higher chance of getting leukemia
  8. Feb 26 by
    Quote from brithoover
    RA children have about a 2-4 times higher chance of getting lymphoma type cancer and Down children have a 20 times higher chance of getting leukemia

    See what you can find out when you search? Gold star, brithoover.
    Now, OP, what does that mean? Compared to ... ?
  9. Feb 27 by
    Good work, brithoover!

    References for those?
  10. Feb 27 by
    I work in peds heme/onc. We study from APHON text: Essentials of Pediatric Hematology/Oncology Nursing
    GrnTea likes this.