Insulin Question

  1. Can anyone tell me how much Insulin has to be given (SQ) in a normal healthy adult to cause death? had an incident happen I am curious about!! :angryfire
    Thanks in advance for your time.
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  2. 7 Comments

  3. by   athomas91
    individual dependent. - there is not a set dose that is lethal
  4. by   Lilith
    The recommended dosage is 0.5-1.0U/kg/day. Toxicity from a hypoglycemic reaction would depend on a number of factors including kidney and liver function, how much the person had to eat, or continued to eat after the injection, rate of absorption relative to percentage of SC fat etc. Also depends on what type of insulin....I'm assuming we're talking about Regular, where a rapid, immediate blood sugar fall could be a problem. IV administration recommends pushing no more that 50U over a 1 minute period....if that gives you an idea of where the danger zone might lie.
  5. by   Blackcat99
    :chuckle If you are planning to kill someone with an insulin overdose make sure they are truly diabetic! I remember hearing about that prison nurse who killed her husband with an insulin overdose. The only problem was that he was not a diabetic and so she got busted and went to prison. :chuckle
  6. by   sharann
    How much did the person in the incident receive and were they in DKA or diabetic at all?
  7. by   Lilith
    Quote from Blackcat99
    :chuckle If you are planning to kill someone with an insulin overdose make sure they are truly diabetic! I remember hearing about that prison nurse who killed her husband with an insulin overdose. The only problem was that he was not a diabetic and so she got busted and went to prison. :chuckle
    WAY too funny....I wonder if she used to list "strong critical thinking skills" on her nursing resume......
  8. by   caroladybelle
    Like Morphine, it is pretty dependant on the individual. I have had a nursing instructor that tooh around 200u Q4, and still crank high blood sugars. And then I have had 4u crash someone out.
  9. by   mbess02
    For a type 1 diabetic, they are much more insulin sensitive than a type 2, and less insulin will cause more violent hypoglycemia more rapidly. This is also because the type 1's counterregulatory process (ie release of glucagon) is impaired compared to a type 2 or a regular patient.

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