I've had several pts with multiple different diagnoses and admitting problems whose INR continued to increase daily despite holding Lovenox, Coumadin, etc.
One pt had daily INRs of 6.3, then 7.1, then 7.4. All the while holding any meds that would increase it. Docs wanted to wait and see if it would go down on its own before treating it.
Why would an INR increase like this, even without administering anticoagulants?