What is the toughest part of nursing?

Am curious - if you had to pick one thing related to the nursing practice that is the toughest, what would it be?

[MoLo]

Get into administration, or on committees!  It takes you away from patient care somewhat when you step into management roles, but then you can enact a lot of change, probably not everything you want, but a lot!  Best decision I made in my nursing career. Lasted 16 years until it was too much, but a lot of change happened.

[MoLo]

Then I am sad that your organization is not taking advantage of the front line knowledge and expereince. I was lucky.