# What is 'Therapeutic Dose' in medical calculation?

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Hey guys,

I'm studying for my exam and I'm a little bit confused with therapeutic dose's calculation. I have this question:

A child receives 450 mg of Augmentin 3 times a day. His weight: 16 Kg. What is the therapeutic dose?

1. 84

2. 28

3. 30

This is my first encounter with this kind of problem.

Thanks,

Michal.

Specializes in OR, Nursing Professional Development.

The therapeutic dose is those amounts of the drug where it is enough to be effective but not so much that it becomes toxic. A good drug book should be able to tell you the therapeutic range, which is calculated using the weight. The correct answer will fall between those two numbers.

Specializes in Surgical Intensive Care.

Your drug book should give you a range specific to the drug in mg/kg/day. For example, 10-15mg/kg/day (note: this is not the therapeutic range, it is simply an example). Also recognize that you may see it as a total DAILY dose. According to the frequency of administration, the daily dosage may be divided into multiple doses throughout a 24 hour period. Don't get these confused as being one in the same.

If you can find the therapeutic range, calculate the lowest therapeutic dosage for mg/kg/day and the highest therapeutic dosage for mg/kg/day. If your medication order (or ordered dosage) falls equal to, or between, these two numbers then the medication is safe to give and therapeutic.

Good Luck!