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This is the second in a series about the gut microbiome. Recent research has implicated the microbiome in colitis, IBS, obesity, depression, autism, cancer, Alzheimer’s and diabetes. This article explores the role of the microbiome in weight management. We are familiar with traditional reasons for weight gain: unhealthy diet, sedentary lifestyle, unlucky genes. Recent studies suggest that billions of gut microbes may also play a role.