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Discussion

Trial off of PGE

Have you ever had a baby with a ductal dependent lesion that has been trailed off of PGE? If so, how was the experience? What was the reason they did it?

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    Sure, it depends on the infant in question & the type of defect they have, plus any "extra" openings or various anatomy differences that may help them out. PGE1 is not a benign medication. It can cause apnea (requiring intubation), bleeding, flushing, etc etc. If the baby doesn't need it while they await for their cath procedure or surgery, that's great. I've seen only a couple of cases that tolerated it, but the rest of them only lasted about 12-24 hours.

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    Thank you. It was for a coarctation of the aorta. The baby ended up having the trial off in our PICU and I believe surgery the next day.

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