Propofol in the ICU

[Pharmahaulic]

I know there's a recommendation to not use for more than 48 hours at a time but many other people I know who work in ICU's and such said that they will use it for weeks at another. Also, other sources said it can be used for extended periods of time if the benefits outweigh the risks. What is your take?

[worldsfinest]

are you a member of AACN? go there and search "propofol" and there's a scholarly article on the syndrome.

[dread_pirate_roberts]

48 hours is the recommendation, but as you might know - every person and patient is different. They metabolize differently, and have compounding comorbidities that will make them more susceptible to PIS. The best way to answer this question for yourself is do some research on your facility's UpToDate or Micromedex.