Premarin IV

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Need some quick help please. My wife may need Premarin IV to help control bleeding. I have never given it in 19 years of working in critical care/ER, and I need to know how it is given - IV push vs. infusion? Side effects?

Thanks.

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Premarin can be given IV/IM 25mg mix with 5ml sterile water. It can be given once with a repeat in 6 to 12 hours if needed. It can be put in minibottle, but not necessary. Our facility gives it 25mg IV every 4 hours for up to 24hours, if needed. It will cause flushing if given too fast.

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