INR & Blood coagulation studies!!

  1. hey everyone! im new to this site,
    wondering if anyone could help ive got an assignment part of which focus's on INR...i was wondering why its not advisable to do it in the AM of the day (from what i have been told this isnt the right thing to do)! also wondering what is the purpose for doing blood coagulation studies in a person suspected of a PE (pulmonary embolus)!! my searching for info has proved difficult!
    thanks for any help in advance
  2. Visit milly85 profile page

    About milly85

    Joined: Oct '06; Posts: 2


  3. by   wahoofan
    If a pt. has a PE, then more than likely they will be started on anticoagulants......the PT,PTT, and INR are needed prior to beginning those meds in order to have a baseline value and be able to determine how much Heparin or Coumadin to use.
  4. by   Daytonite
    hi, milly85!

    i've not heard that the pt/inr not be done early in the day. i know that coumadin, the anticoagulant, which these tests assess the effectiveness of, should be given in the late afternoons. the reason has to do with the amount of time between the administrations of the medication, the blood levels of the anticoagulant, and the time the blood specimen is going to be taken. if the coumadin is given in the morning, then the pt/inr will need to be drawn in the late afternoon to avoid getting an inaccurate reading.

    a embolus is a blood clot. initial coagulation studies may show that the patient has some sort of physiological problem with the natural clotting mechanisms that is causing blood clots to form in his/her body. however, upon discovering a pulmonary embolus, the standard medical treatment is to start the patient on anticoagulation therapy as soon as possible to prevent the embolus from becoming larger and prevent the formation of more emboli. these drugs are monitored by the coagulation studies and inr. their doses are titrated according to the lab data provided by pt/ptt and inr tests. when a patient is started on heparin, it is not usual for the doctor to have a ptt drawn every 4 hours until an adequate therapeutic anticoagulation response is seen in the labwork.

    your question gets asked a lot. here are a number of old threads about these lab tests. within one or two of these threads are links to lab tests online where you will find explanations about each of the coagulation lab tests.

    welcome to allnurses!
  5. by   solumedrol
    Interesting.. Thanks for the info..