chem q's..help how to do

49) Chloroquine is used to treat malaria. Studies have shown that an effective dose for children is 3.5 mg per kilogram (3.5 mg/kg) of body weight, every 6 hours. If a child weighs 12 kg, how many milligrams of this drug should be given in a 24 hour period?
53) a. A vial contains 25 mg/mL of a particular drug. To administer 15 mg of the drug, how many milliliters should be drawn from the vial?
b. A patient is to receive 50 cc of a drug mixture intravenously over a 1 hr time period. What is the appropriate IV drip rate in gtt/min?
Thank you! 

Jun 19, '09Occupation: RN From: US ; Joined: Aug '08; Posts: 28; Likes: 1949. First you have to figure out the mg needed. You need to take the mg x childs weight. 3.5mg x 12kg= 42mg per dose. If you are giving it every 6 hours during a 24 hour period that would be 4 doses. So you take
42 mg x 4 = 168mg
50. a. There is a formula for this one. It is desired divided by what you have multiplied by the amount. So you need 15mg but it comes 25mg per 1ml. So you would take 15 divided by 25 multiplied by 1ml = 0.6 ml's
b. This one depends on the drip factor of your IV tubing. Lets say your IV tubing that you are using has a drip factor of 10. You would need to use this formula: amount ( in this case 50ml's) multiplied by drip factor ( we will say it is 10) divided by the number of minutes it will infuse ( 60 minutes) = 8.3 drops per minute rounded down to 8 per minute.
I hope this helps! 
Jun 19, '09Specialty: med/surg, telemetry, IV therapy, mgmt ; Joined: May '05; Posts: 15,027; Likes: 8,97549) chloroquine is used to treat malaria. studies have shown that an effective dose for children is 3.5 mg per kilogram (3.5 mg/kg) of body weight, every 6 hours. if a child weighs 12 kg, how many milligrams of this drug should be given in a 24 hour period?
3.5 mg/kg (dose desired) x 12 kg (weight of child)/6 hours (dose desired) x 24 hours (amount of drug desired over time) = 168 mg (amount to give)53) a. a vial contains 25 mg/ml of a particular drug. to administer 15 mg of the drug, how many milliliters should be drawn from the vial?
15 mg (dose desired)/25 mg (dose on hand) x 1 ml (amount the dose on hand comes in) = 0.6 ml (amount to draw from the vial and give the patient)b. a patient is to receive 50 cc of a drug mixture intravenously over a 1 hr time period. what is the appropriate iv drip rate in gtt/min?
while the problem doesn't give you a drop factor for the iv tubing, it tells you that 50cc needs to infuse over 1 hour, or 60 minutes. the easiest tubing to use and calibrate for a job like this is pediatric, or microdrip tubing which has a drop factor of 60 gtts/ml. the drip rate for pediatric, or microdrip tubing is always the same as the ml/hour that the iv would infuse at. so using 60 gtt/ml tubing this would infuse at 50 gtts/min.
50 ml/hour (infusion rate) x 60 gtts/ml (drop factor of iv tubing) x 1 hour/60 minutes (conversion factor) = 50 gtts/minute (drip rate)if you use standard 15 gtt/ml tubing you would get:
50 ml/hour (infusion rate) x 15 gtts/ml (drop factor of iv tubing) x 1 hour/60 minutes (conversion factor) = 12.5 gtts/minute, rounded off to 13 gtts/minute (drip rate)i was nursing back in the days before iv pumps. believe me, it is much harder to calibrate 13 gtts/minute than 50 gtts/minute. 