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Discussion

Magnesium Electrolyte

I was wondering if hyper or hypoparathyroidism causes Hypomagnesia? 

In my med surg book, it says hyperparathyroidism does but in my NCLEX study material it says that hyperparathyroidism causes hypomagnesia. 

Also, are calcium and magnesium inversely related? cause I thought it was calcium and phosphorus 

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18 minutes ago, tacosforlife said:

I was wondering if hyper or hypoparathyroidism causes Hypomagnesia? 

In my med surg book, it says hyperparathyroidism does but in my NCLEX study material it says that hyperparathyroidism causes hypomagnesia. 

Also, are calcium and magnesium inversely related? cause I thought it was calcium and phosphorus 


I hope you’ll find this useful  


https://www.ncbi.nlm.nih.gov/books/NBK500003/
 

 

I am in the dialysis field and we look at primarily secondary HPT.  PTH secretion is tied to serum calcium levels but magnesium can exert a similar effect.  Low levels (hypomagnesemia) can cause an increase in PTH secretion leading to low calcium levels especially in our population because their kidneys don't convert Vitamin D2 to D3 which is the active form (simplified version!) and they cannot absorb CA from the gut..  If a patient has an extremely low magnesium level PTH secretion slows and the patient can become even more hypocalcemic.  So for someone with severely low magnesium levels, the pt. would most likely have a normal to low level of PTH secretion.  With just low levels, the PTH rises.  For secondary HPT, it is calcium and phosphorus that are the major drivers of increased PTH levels.  If phosphorus is too high, the parathyroids increase production to bring calcium levels in line with phosphorus.  The body looks for calcium in the easiest place to find it - the bones.  Thus, our patients can have osteopenia and risk calciphylaxis if uncontrolled.  

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