IV cyclizine time between doses

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Firstly - hi to all as this is my first post 😃

IV cyclizine is normally written up PRN and dosing is written as TDS. I find this pretty non specific. Orally it can be given every 4-6 hours with a max dose of 150mg (so it's 50mg TDS).

A lot of the nurses on my unit get confused by this and refuse to give IV cyclizine unless 8 hours has passed (because it just says TDS they split 24h in to 3 - giving them 8 hours). However, if my patient complains again of nausea after let's say 5 hours I will happily give them another dose.

So I guess my question is - what is the minimum amount of time between doses of IV cyclizine?

An additional question - how quickly is the onset and what is the duration ? (I can find this information for oral (oral kicks in after around an hour and lasts around 4h - correct?) but not IV)

Many thanks.

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Specializes in ER/Tele, Med-Surg, Faculty, Urgent Care.

What is TDS? Have never heard this acronym before.

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It means three times per day. I think it stands for something in Latin. Sorry I assumed that was used all over the world.

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Specializes in ER/Tele, Med-Surg, Faculty, Urgent Care.
It means three times per day. I think it stands for something in Latin. Sorry I assumed that was used all over the world.

No. In the US, we use TID (latin for "ter in die". What country are you in?

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It's for "ter die sumendum". That's in the UK.

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