Inappropriate hypotonic IV

[walkiez]

Anyone give me a hand on what the likely outcome would be on administering an inappropraite hyponic solution IV. What would happen to blood osmolarity, what would be the fluid shifts, ADH secretion and urine production

[Sirius Black]

I did something like that in a tute earlier this year.

This is what I have in my notes:

ECF volume increases, Blood osmolarity/ECF concentration decreases (b/c fluid moves intracellur), ICF volume increases causing cellular swelling.

Urine/kidney changes:

Blood volume increases, BP increases therefore glomerular hydrostatic pressure and GFR increase.

Reabsorption decreases, the secretion is unchanged. Urine volume increases and urine concentration decreases. So there is lots of water in the urine.

Secretion of ADH would decrease (it's stimulated in response to rise in blood osmolarity - here the blood osmolarity is decreased).

Hope that's what you were after.

[Daytonite, BSN, RN]

very simply, hypotonic solutions are weak enough that the osmalarity of the cells of the body are stronger and able to pull that fluid into them. if not corrected, more and more fluid gets pulled into and trapped in the cells. here are a couple of articles that mention the effect of hypotonic iv solutions on the body.

http://www.nursewise.com/courses/iv_hour.htm - this is an article about intravenous therapy and electrolytes. it mentions the affect of hypotonic solutions on the body several times

http://enw.org/electrolytes.htm - water and salts: maintaining the internal seas in harmony

[USAstudent]

Somebody told me a great trick for remembering the different effects of hypo vs hypertonic solutions. Hypo-remember the "o" looks like a swollen cell, hyper-remember that the "e" looks like a shruncken cell. Of course the degree of effect would depend on the situation...fluid status of the patient/ degree of hypotonicity of the solution, etc.