Help with ARF secondary to AGE

[ails]

Hi everyone! My groupmates and I are currently working on a case study about a patient diagnosed with Acute Renal Failure secondary to Acute Gastroenteritis. For the pathophysiology part, how can AGE lead to ARF? Our patient has hemorrhage. From the Brunner Med-Surg book by Smeltzer [et al.], it said that hemorrhage is one of the causes of Prerenal ARF. How exactly does it happen?

My presumptions are the gastrointestinal inflammation + hemorrhage compresses the kidneys and therefore causes poor GFR. Our patient's urinalysis shows increased BUN & Crea levels in the urine. If this is the case, can this still be elaborated?

Thanks a million in advance!

Ails

[Daytonite, BSN, RN]

the blood loss caused by severe gastroenteritis results in hypoxemia because of the decreased circulating blood volume. the diminished blood volume can't carry the normal amounts of oxygen that the cells of the body need to keep its regular processes going. the tissues of the kidney are more sensitive to the effects of hypoxemia than other body cells and the renal tubules succumb to ischemia and die. acute renal failure follows. also, the kidney is a highly vascular organ. a diminished blood volume means less blood is circulating through this organ.

[ails]

Thanks very much for your help for the third time :)