Handling prefilled syringes

[adjalian]

Dear all,

I am working on handling instructions for prefilled propofol syringes and I am stuck with a question only an experienced user may know. Therefore, I dare asking you. Maybe you can help me answering the two short questions below.

I am trying to find out how the following situation is handled in clinical practice:

When propofol is given as a bolus, will a syringe with a scale in 0.5 ml increments be sufficient to measure the intended size of a bolus or would a syringe with smaller increments, e.g. 0.2 ml, be necessary?

My second question concerns the areas of use for prefilled syringes with 10, 20 and 50 ml. I understand the small ones are for induction and procedural sedation, the large one for anaesthesia and long term sedation. Did I miss anything?

Thank you very much for your kind help

Sylvie

[wtbcrna, MSN, DNP, CRNA]

Propofol is usually measured in 1ml increments or more appropriately by the milligrams given. Generally, a prefilled propofol syringe is going to contain 20ml for anesthesia purposes. We generally use the 50ml or 100ml bottles of propofol when running a propofol drip.

[adjalian]

Thank you, that helps me!

[chemokine]

Propofol spoils (like milk) so it comes in sealed bottles that must be drawn up. I've never seen it prefilled in a syringe I figured for this very reason. It is good for only 12 hours after being drawn up.

[wtbcrna, MSN, DNP, CRNA]

Propofol — Pharmedium - pharmacy outsourced compounding. You can almost any commonly used drug in a prefilled syringe including propofol.