Venous Urokinase for DVT on Med-Surg Floors

  1. Last edit by susanmary on Aug 4, '03
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    About susanmary

    Joined: Dec '00; Posts: 826; Likes: 16


  3. by   Sleepyeyes
    We usually use Lovenox, ABT's, moist heat, and bedrest for DVT's.
  4. by   renerian
    I work in home health and have started lovenox for the acute period. The same that sleepy posted. Saw a sharp rise in that drug use in the last six months before I left home health in August.

  5. by   Agnus
    Urokinase should be administered in only very controlled settings. I have used a very tiny amt to unclog PICC lines. Then withdrew the medication from the line after the clot was disolved.
    However, I believe this should be administered only by a physician when used to break up clots in vessels. Generally I do not see it used for DVT as the risk is generally considered greater than the benefit in this case. It is usually reserved for clots in more critically dangerous locations.
    Last edit by Agnus on Oct 23, '02
  6. by   Beetlejuice
    Ya know, urokinase is not specific. It works on all thrombi, not just the venous ones and not just the ones blocking vessels. In my opinion, your taking too great a risk administering this outside a stepdown/ICU setting.
  7. by   susanmary
    I appreciate the input. Currently, DVTs being treated with either: iv heparin protocal/coumadin; lovenox; or fragmin. Bedrest with leg elevation until therapeutic. I'm still curious if ANYONE out there on the non ICU/SD floors admit patients with UROKINASE (venous) infusing.