The soap and waterless hand sanitizer they provide at my workplace is not getting along so great with my hands. They are usually rough and sometimes even red from washing so much. I've never tried a soap that didn't do this, by the way.
I use Gold Bond Ultimate Healing lotion, and that seems to help a little. Moreso than anything else I've tried. But I'm interested in what others do. I hate the thought of there being lots of cracks (portals of entry for infection) in my hands. I keep short nails, etc, but my cuticles get really dry, too.