Evidence,heparin or ns flush

  1. I remember reading,but I dont know where,that flushing a hep.lock/saline lock, to keep the vein patent,with NS is just as effective ,and cheaper ,than flushing with heparin flushes. Does any one know where I can find some evidence for this?
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    Joined: Jun '01; Posts: 430


  3. by   smiling_ru
    You can just run a search on some of these articles.

    Goode, C.J., and others: A meta-analysis of effects of heparin flush and saline flush: quality and cost implications, Nurs Res 40(6):324-330, 1991.

    Gyr P and others: Double blind comparison of heparin and saline flush solutions in maintenance of peripheral infusion devices, Pediatr Nurs 21(4):383-389, 366, 1995.

    Hanrahan, K.S., Kleiber, C., and Fagan, C.: Evaluation of saline for IV locks in children, Pediatr Nurs 20(6):549-552, 1994.

    +Heilskov J and others: A randomized trial of heparin and saline for maintaining intravenous locks in neonates, JSPN 3(3):111-116, 1998.

    Kleiber, C., and others: Heparin vs. saline for peripheral IV locks in children, Pediatr Nurs 19:405-409, 1993.

    +Kotter RW: Heparin vs saline for intermittent intravenous device maintenance in neonates, Neonat Network 15(6):43-47, 1966.

    LeDuc K: Efficacy of normal saline solution versus heparin solution for maintaining patency of peripheral intravenous catheters in children, J Emerg Nurs 23(4):306-309, 1997.

    +Lombardi TP and others: Efficacy of 0.9% sodium chloride injection with or without heparin sodium for maintaining patency of intravenous catheters in children, Clinical Pharm 7(11):832-836, 1988.

    +McMullen, A., and others: Heparinized saline or normal saline as a flush solution in intermittent intravenous lines in infants and children, MCN 18(2):78-85, 1993.

    *Mudge B, Forcier D, and Slattery MJ: Patency of 24-gauge peripheral intermittent infusion devices: a comparison of heparin and saline flush solutions, Pediatr Nurs 24(2):142-149, 1998.

    +Nelson TJ & Graves SM: 0.9% sodium chloride injection with and without heparin for maintaining peripheral indwelling intermittent-infusion devices in infants, Am J Health-Syst Pharm 55:570-573, 1998.

    +Paisley MK and others: The use of heparin and normal saline flushes in neonatal intravenous catheters, Pediatr Nurs 23(5):521-527, 1997.

    Robertson J: Intermittent intravenous therapy: a comparison of two flushing solutions, Contemp Nurs 3(4):174-179, 1994.
  4. by   globalRN
    It is so standard now that heparin locks are now referred to as saline locks...injection caps etc