docusate sodium vs saline laxative

Posted

Docusate sodium works by osmosis to draw water into the colon. How are the mineral citrate solutions (stool softeners) not working by the same mechanism?

combinate

57 Posts

I equated the mineral citrates with “saline laxatives”. Is that right? And, are those also the same as “Saline cathartics”?

loveofrn, BSN, RN

Specializes in MICU. Has 3 years experience. 347 Posts

Hint:

Hypertonic and hypotonic

combinate

57 Posts

It seems like Docusate sodium and the citrates could both be hypertonic and work by osmosis. ?

combinate

57 Posts

ok

How about the second post?

Esme12, ASN, BSN, RN

Specializes in Critical Care, ED, Cath lab, CTPAC,Trauma. Has 42 years experience. 4 Articles; 20,908 Posts

If you look at the links I provided the answer is there....I thought Ducosate was anionic

Edited by Esme12

SierraBravo

Has 3 years experience. 547 Posts

Docusate sodium works by osmosis to draw water into the colon. How are the mineral citrate solutions (stool softeners) not working by the same mechanism?

Actually, docusate does not draw water into the colon. The MOA of docusate is by reducing the surface tension of the oil-water interface of the stool, thus the stool becomes "softer". An example of something that would draw water into the colon would be lactulose, a synthetic sugar.