dexmetatomadine

[jbro]

is anyone using dexmetatomadine in their practice, if so how, and what kind of results are you seeing in terms of decreased mac and opiod use? we discussed it a little in class and seems like a good drug, but i haven't heard of anyone using it much and i was wondering why.

[Phishininau]

This is a central alpha 2 agonist like Clonidine, is it not?[/quote']

Yes and no. It is a central A2 agonist, but at high doses (>2mcg/kg) it loses its selectivity and you get an A1 agonism that will cause hypertension and reflex bradycardia.