Ketamine manufacturer

  1. Hi all,

    I'm writing a paper for my Pharm class on ketamine in anesthesia. Can anyone tell me who the manufacturer is? I need to get the drug monograph. I will search online, but I thought I'd try here too.
    I would like to hear from some of the CRNAs/MDAs who use Ketamine in practice. In which cases do you like to use Ketamine? What are the pros and cons of using this drug? Thanks in advance.

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    About TraumaNurse

    Joined: Sep '02; Posts: 637; Likes: 11
    Trauma ICU/ SRNA


  3. by   lasvegas4211
    Ketalar is the trade name, one manufacturer is Pfizer.
  4. by   nilepoc
  5. by   UCDSICURN
    I'm not a CRNA nor MDA but our Burn ICU uses it for large burn dressings and we use it for large wound packing. I personally don't know much about it, as I haven't used it nor am I certified in doing so (Must be certified at my facility to use it.), but what I do remember reading is that during emergence the patient needs to be left alone, unstimulated or they can have some pretty nasty psychological side effects.

    Any of the pro's, please chime in. Got my curiosity going.

    Donn C.
  6. by   nilepoc
    I had a patient wake up, grab his chest, yell I am going to die, my heart hurts. He then "passed" out. You want to see PACU nurses run for cover, have your patient do that. We did everything, labs, EKG.......... and all were clear.

    One half hour and eight of versed later, the patient was back to normal and did not remember the incident. From this experience and many others, my desire to use ketamine has been squashed. I really don't like it right now.
  7. by   kmchugh
    Ketamine is a long way from my favorite drug, but I will use it when the situation seems to call for it. Ketamine does not have the cardiovascular depressive effects that Propofol has, so I do like to use it in patients for whom CV depression would be a bad thing. It also has some analgesic properties, so I have used it in the past to sedate hip fx patients while they are turned to place a spinal or epidural. In fact, the drug almost seems tailor made for this use. Generally, I find if I pretreat the patient with versed, I have no problems with some of ketamine's nastier effects.

    Kevin McHugh
  8. by   NCgirl
    I haven't used Ketamine yet, but have covered it in class. Seems to be popular in ODS for mentally retarded adults, to chill them out for induction. Also good for transient pain, like a closed reduction in ER, etc. Important thing to remember, like Kevin said, is it's CV effects. Even though you may see HR and BP go up, it is a negative inotrope. You see vital signs rise due to a sympathomimetic response. Good luck in your paper!
  9. by   smiling_ru
    It is one of my favorites for "deep sedation". Start a propofol drip, once the patient is sedated give 5mg of ketamine, redose to respiratory rate/depth. The propofol will counteract the "bad" effects of ketamine and the ketamine keeps the heart rate, blood pressure and respiratory rate at an acceptable level. I believe this technique is frequently used in outpaitent plastic surgery centers. One place used this technique for total hips!! The surgeon obviously had to put in an adequate amount of local, but it worked.
  10. by   gaspassah
    ketamine causes a release of endogenous catacholamines. ie, bronchodilation, increase hr, increase bp.
    not a bad drug for severe asthmatics. (however we were taught that pentathol is ok for asthmatics if you get them deep enough fast enough.)

    disassociative anesthetic. keeps one part of the brain from talking to another.
    depending on dose you can get sedation but the patient can maintain their own airway.
    causes hallucinations on emergence, not good for ptsd, psych pts.

    my daughter got it once, and she had nightmares for several days after.
    just a few things i remember so far about the drug. i havent used it in clinical but i the crna's i've worked with dont like it unless they need to use it by necesity.
  11. by   TraumaNurse
    Very helpful..thanks guys!
  12. by   Brenna's Dad
    I've used it a few times for MAC cases. 10 mg Ketamine in 20 cc Propofol, titrated to effect. However, I really like Alfentanil better. 500-1000 mcg in 20cc Propofol, titrated to effect.
  13. by   calgal
    Ketamine was regularly used with pediatric patients in a large pediatric setting in the Bay area where I used to work. Using Ketamine on children older than 4 years old was generally discouraged because of the unpleasant psychological side effects (both for the child and his/her parents).