Cardiac Biomarkers?

[LuvScrubs2, BSN, RN]

I want to make sure that I am understanding this concept. I am currently taking critical care nursing....

Cardiac specific : which is the troponin I & the CKMB which will both be released during cardiac muscle injury. but at the same time troponin can be delayed as well?

can anyone explain to me why this occurs?

also can someone explain the Nonspecific : myoglobin,CK troponin T significance.

I would appreciate any assistance given.....

[Daytonite, BSN, RN]

ck-mb is the abbreviation for "creatine phosphokinase muscle and brain" and are the isoenzymes found in the heart. normal levels are less than 4 - 6%. they will increase when there has been injury because those enzymes are released into the bloodstream. levels increase in predicted time frame levels, and the specific isoenzyme that is present can determine the exact location of the tissue that has been damaged.

troponins are several specific proteins that are only detectable when there has been an mi or myocardial cell damage.

troponins are a generalized marker telling you an mi or myocardial damage has occurred. ck-mb is a more specific test telling where and when.

http://www.labtestsonline.org/unders...ckmb/test.html

http://acronyms.thefreedictionary.com/ck-mb

http://www.webmd.com/heart-disease/c...studies?page=2

http://adam.about.com/encyclopedia/c...zymes-test.htm

http://www.labcorp.com/datasets/labc...o/ri028700.htm

http://www.medicinenet.com/script/main/art.asp?articlekey=89510 - biomarkers predict heart deaths

http://adam.about.com/encyclopedia/infectiousdiseases/heart-attack.htm - heart attack

http://www.labtestsonline.org/understanding/analytes/troponin/test.html

[LuvScrubs2, BSN, RN]

Thank you Daytonite!!!!!!!