Can some one develop an allergy to PPD?

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Is it possible to build up an allergy to PPD? Granted I have had approx 12 TB skin tests since 2000 and will get one every year for the rest of my life; is it possible to develop and allergy to PPD? This is the second time I have gotten a red raised area just under the size of a quarter the evening after getting a TB test. It looks exactly the same as last time and last time it was gone the next day and stayed gone. It has happened again but this time I have a runny nose; which could just be coincidence. I took a picture of it but I did not know if I could post it; I am not asking for medical advise...I am just curious.

There is a possibility of an immediate hypersensitivity reaction, NOT a +PPD, usually due to an allergy, that may develop within 24 hours of placement, which will cause swelling, itching, or, in extreme cases, symptoms of anaphylaxis. The delayed hypersensitivity reaction, a +PPD, which can include ulceration, vesiculation, etc. (in addition to classic induration), has an onset that usually peaks 48-72 hours later. The brand used may explain different results in different years (Tubersol vs. Aplisol). My favorite explanation of this can be found on p. 1388, par. B of http://www.cdc.gov/tb/publications/PDF/1376.pdf

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Specializes in Critical Care.

THANK YOU!!!

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Specializes in NICU, PICU, PACU.

Yes you can! I had a horrible reaction to my TB test and then my flu shot in the same year. I had a huge, and I mean huge ugly wheal from both! I had to go to the ER and get a steroid shot for the flu one, my arm looked awful! Now I have to make sure everything I get is thirmosol free.

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