Burns and hypoproteinemia

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Why do burns cause an increased flow from capillaries in nonburned surrounding tissue, and what connection does this have with hypoprotienemia? Supposedly hypoprotienemia causes the fluid from around the burn to collect at the burn site, but can someone please explain how this works? Thanks!

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Specializes in Critical Care, ED, Cath lab, CTPAC,Trauma.

HI! Welcome to AN! The largest online nursing community!

We are happy to help! What semester are you? What does your textbook say?

We are always happy to help but we ask ALL students to post what their r4esearch has revealed first so we can jump in and help you find the answer you are looking for or where to correct you if you are not heading in the right direction. It is important for ALL students to know how to find answers and research disease processes as this will be a big part of your everyday working life.

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Why do burns cause an increased flow from capillaries in nonburned surrounding tissue, and what connection does this have with hypoprotienemia? Supposedly hypoprotienemia causes the fluid from around the burn to collect at the burn site, but can someone please explain how this works? Thanks!

Someone correct me if i'm wrong:

Tissue necrosis and destruction of blood vessels can inhibit blood flow to the damaged area, the body has a natural cell mediated response through inflammatory pathways when it sences tisue damage, this response includes opsonization, cytokines, bradykinins, ILs and histamines released into surrounding tissues. This is why blood flow is increased...it aids in the healing process.

Low protein is caused by the amount of stress being put the body to repair itself. There are so many cells that have been destroyed that the body is signaled to make new ones, this includes WBC's, Platelets, new blood and blood vessels and all the skin and tissue that has been destroyed. As the body goes into this state it uses up TONS of the protein being stored in the system to rebuild. This will result in a drop in the serum protien and thus a drop in serum osmo. Fluid moves to interstitial spaces. and voila you have tons of 3rd spacing.

Please feel free to correct anything I have said.

-ND

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Specializes in Critical Care, ED, Cath lab, CTPAC,Trauma.

Noctor Durse has been very nice to you.

AN feels strongly that students post what they think, or what their research has revealed to them, and their work on a math problem so we can best answer the student questions appropriately without just giving the answer.

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