adrenergic receptors

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help please i need to find a way to remember what the receptors do..i've been reading my textbook and going over my notes but i'm getting confused.i'm getting the hang of it a little.but i just want to make it organized so it can be clear to me.anyone who took pharm 2 already and succeed your tips would be greatly appreciated

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Okay, I did a bit of studying and I can offer a little assisstance hopefully.

Parasympathetic System The two neurons are cholinergic. The receptors are nicotinic and muscarinic. The neurotransmitter received is acetylcholine for both neurons

Sympathetic System The first neuron is cholinergic and the second is adrenergic. The receptors are nicotinic and adrenergic (adrenergic is further divided into A1, A2, B1, or B2) The neurotransmitter received for nicotinic receptor is acetylcholine, and the neurotransmitter received for adrenergic receptor is norepinephrine.

Acetylcholine Is released from preganglionic neurons (1st neruon) in response to a stressful event. It also stimulates postganglionic neurons (the 2nd of two) causing them to release epinephrine and norepinephrine. It is inactivated by cholinesterace.

I know it isn't much, but I hope it helps out.

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As I stated above, adrenergic receptors are divided into alpha 1, alpha 2, beta 1, and beta 2. (You will find both alpha and beta receptors in most effector organs.)

Stimulation of alpha 1 receptors causes vasoconstriction of smooth muscles walls and also blood vessels

Stimulation of alpha 2 receptors inhibits NE release

Stimulate a beta 1 receptor and your heart will beat faster and with more force.

(these receptors are located mostly in the heart) * You only have 1 heart so think beta 1

Stimulate a beta 2 receptor and your bronchioles will dialate and your blood vessels will relax.

*You have two lungs so think beta 2

Adrenergic drugs work by stimulating adrenergic nerves either by mimicking the action of NE, or by stimulating its release. They are used for acute attacks of bronchial asthma, cardiac arrest, and allergic reactions. They are also used in nasal decongestants.

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Receptor Sites

alpha-receptor

iris dilation

Vasoconstriction

intestinal relaxation

intestinal sphincter contraction

bladder sphincter contraction

beta-receptor

cardioacceleration (b1)

vasodilation (b2)

intestinal relaxation (b2)

uterus relaxation(b2)

bronchodilation (b2)

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thank you all.im getting the hang of it lots of reading

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