H5N1, Bird Flu Updates - page 22

by indigo girl

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Tracking Bird Flu Cases Bird flu deserves its own thread for tracking suspected and confirmed cases. It's not the pandemic virus, but it is still an ongoing and significant threat because of its virulence. As Margaret Chan,... Read More


  1. 0
    Pandang, Indonesia

    http://afludiary.blogspot.com/2011/0...-bird-flu.html

    Quote from afludiary.blogspot.com
    Over the past couple of weeks residents in at least 8 districts (Padang Barat, Padang Utara, Padang Timur, Padang Selatan, Kuranji, Lubuk Begalung, Koto Tangah and Nanggalo) have reported numerous sudden deaths among their poultry holdings.

    Last week we learned of two children in the city who had been hospitalized with `bird flu-like symptoms’ at M Djamil hospital, beginning on February 26th.

    Admittedly, many other illnesses can mimic bird flu, including seasonal flu. So the presence of clinical `flu’ symptoms, even in conjunction with exposure to infected poultry, is hardly conclusive.

    That number has now grown (see Padang: Bird Flu Suspect Cases Increase To 5), although we have yet to receive official word on their test results.

    At least one subject reportedly has tested positive via a `rapid test’ (see BFIC Padang, West Sumatera ::: A bird flu suspect rapid tests positive).
  2. 0
    Tripura, India

    http://news.in.msn.com/national/arti...mentid=5000310

    Quote from news.in.msn.com
    Tripura government has launched fresh culling operation at Bridrinagar gram panchayat areas, close to government-run R K Nagar Farm where hundreds of ducks died of avian influenza last month.
    As many as 116 birds were culled at Bridrinagar, 7.5 km from here yesterday, Joint Director of Animal Resource Development Department (ARDD) Jyotirmoy Chakraborty said today.

    Altogether 16 Rapid Response Teams have been inducted in the culling operation that will cover around 12 to 15 villages of West Tripura district over the next few days, he said.

    There was a report of outbreak of avian flu in another government-run farm at Gandhigram where 380 chicks and ducks died since March 1, he said.
    (hat tip flutrackers/shiloh)
  3. 0
    rosh tzurim, israel

    http://english.pnn.ps/index.php?opti...9666&itemid=30

    Quote from english.pnn.ps
    local sources said a number of turkeys with bird flu had passed the disease to the entire coop, prompting the israeli health ministry to destroy the coop in accordance with protocol, culling 40,000 turkeys. any surrounding coops in a three kilometer area will also be destroyed as a precaution.

    a palestinian source told pnn on tuesday morning that the palestinian ministry of agriculture, veterinary directorate, and other authorities were monitoring everything coming in and out of bethlehem governorate, fearing the possible entry of infected birds.

    this source, unnamed, said that all palestinian farms within a 10-kilometer radius of the infected coop would be thoroughly inspected, but that there was no reason for worry either for palestinian consumers or farmers as appropriate measures were being taken.
    (thanks to crofsblog for the link)

    http://www.recombinomics.com/news/03...32_israel.html

    if this farmer was only hospitalized for a few days, it seems unlikely that he had h5n1 given how sick the infected cases usually become. of course there have been some exceptions, notably all those egyptian toddlers who for some unknown reason survived this flu that generally kills the adults.

    Quote from www.recombinomics.com

    concern that a poultry farmer from kibbutz rosh tzurim in gush etzion contracted bird flu. the man was hospitalized a few days at shaare zedek hospital in jerusalem. the deadly virus was discovered yesterday in one of his kibbutz runs. blood tests of laboratory testing verbalist transferred, and results are expected tonight.

    the above translation describes a suspect h5n1 case associated with an outbreak on a turkey farm, which led to the culling of 40,000 birds. this outbreak follows reports of h5n1 in poultry in palestine.

    if confirmed, this would be the first reported case in israel, and if clade 2.3.2 is confirmed, this would be the first reported human case west of china. all prior human cases (in turkey, iraq, azerbaijan, and egypt) have been the qinghai strain (clade 2.2).
  4. 0
    Egypt - Two More Human Cases Announced

    http://www.who.int/csr/don/2011_03_07/en/index.html

    Notice that the adult woman is in critical condition, yet the two year old is in "good general condition" according to this report.
    This seems to be the pattern for H5N1 in Egypt but no where else.

    Quote from www.who.int
    The Ministry of Health of Egypt has announced two new confirmed cases of human infection with avian influenza A (H5N1) virus.

    The first case is a 32 year old female from Sharkia Governorate. She developed symptoms on 10 February and was hospitalized on 14 February. She is in a critical condition.

    The second case is a two year old male from Kafr Elsheikh Governorate. He developed symptoms on 18 February and was hospitalized on 20 February. He is under treatment and is in a good general condition.

    Investigations into the source of infection indicate that the two cases had exposure to poultry suspected to have avian influenza.

    The cases were confirmed by the Egyptian Central Public Health Laboratory, a National Influenza Center of the WHO Global Influenza Surveillance Network.

    Of the 127 cases confirmed to date in Egypt, 41 have been fatal.
    (hat tip avian flu diary)
  5. 0
    Yesterday WHO confirmed two more H5N1 case in Egypt, one died. . . .

    Egypt Announces More Human Bird Flu Cases
    .


    Avian influenza - situation in Egypt - update 46

    10 March 2011 - The Ministry of Health of Egypt has announced two new confirmed case of human infection with avian influenza A (H5N1) virus and the death of a previously announced case.
    The first case is a 17 year old female from Behira Governorate. She developed symptoms on 27 February and was hospitalized on 1 March. She is in a stable condition.
    The second case is a 17 year old female from Dakahlia Governorate. She developed symptoms on 24 February and was hospitalized on 26 February. She died on 28 February.

    Investigations into the source of infection indicate that the both cases had exposure to sick and dead poultry. Both cases received oseltamivir treatment.
    The cases were confirmed by the Egyptian Central Public Health Laboratory, a National Influenza Center of the WHO Global Influenza Surveillance Network.
    The previously reported case, a 32 year old female from Sharkia Governorate (see update 45), died on 3 March.
    Of the 129 cases confirmed to date in Egypt, 43 have been fatal.
    http://www.who.int/csr/don/2011_03_10/en/index.html
  6. 0
    Bekasi, Indonesia

    http://birdflucorner.wordpress.com/2...5n1-in-bekasi/

    Quote from birdflucorner.wordpress.com
    Biomedical and Pharmaceutical Research Center Laboratory, Indonesia Ministry of Health confirmed an additional H5N1 case. Victim is a 31-year-old female with initial IL, resident of Bekasi, West Java province.

    Victim started to develop illness on 23 February 2011 with signs of fever, coughing and breathing difficulty. She sought for treatment to a private medical practitioner in Bekasi on 25 February 2011. Later she was referred to a referral hospital in East Jakarta, and immediately treated in an isolation unit according to standard protocol. She died in this hospital.

    Risk factor: victim was frequently visiting a nearby market about 200 meters from her house; also many neighbors are rearing ornamental birds.
  7. 0
    dhaka, bangladesh

    http://afludiary.blogspot.com/2011/0...-bird-flu.html

    so a baby survives this in bangladesh, meanwhile adults elsewhere, do not. maybe it is the degree of exposure that makes the difference?

    Quote from afludiary.blogspot.com
    iedcr director mahmudur rahman told bdnews24.com that the human infection was confirmed on monday after testing the samples of saliva and nasal swab of a 13-month-old girl running temperature, who visited an influenza surveillance centre recently.

    the surveillance centre is run jointly by the iedcr and international centre for diarrhoeal diseases and research, bangladesh (icddr,b), he said.

    family members of the child were also examined, said the iedcr director, adding that the minor girl, undergoing treatment in iedcr supervision, was out of danger.
    more commentary on this case:

    http://www.recombinomics.com/news/03...a_toddler.html

    mild cases like this make some of us nervous. you would think that mild cases are good news but, that might not be true.

    and, we wonder about just how much we are not hearing about. it is likely as dr. niman suggests, that at least some of the problem is lack of adequate testing. we worry that the virus is continually adapting to humans through more frequent contact than is being reported or that anyone is aware of.

    Quote from www.recombinomics.com
    ...a link to birds was not described, and treatment with an antiviral was not stated. these two cases strongly suggested that h5n1 infections in bangladesh and india are far more widespread than the two confirmed cases in bangladesh (and no confirmed cases in india).

    recently israel also reported a suspect case with mild symptoms that was not lab confirmed. however, the frequent reports of human cases in egypt strongly suggest that the lack of confirmed cases in israel is surveillance / reporting related, which is also the case for india.

    testing for h5n1 in humans remains abysmal. many countries with high levels of h5n1 in poultry, like egypt or indonesia, rarely test symptomatic cases that do not have a poultry link. milder cases, such as the above case, would rarely seek medical attention, and most who did would rarely be tested for h5n1.

    the recent receptor binding domain change (s227r) reported in h5n1 in japan continues to increase concerns that h5n1 in humans is widespread in patients who are not tested.
    Last edit by indigo girl on Mar 15, '11
  8. 0
    Ismailia Governate, Egypt

    http://www.who.int/csr/don/2011_03_15/en/index.html

    Quote from www.who.int
    The Ministry of Health of Egypt has announced a new confirmed case of human infection with avian influenza A (H5N1) virus.

    The case is a 38 year old female from Ismailia Governorate. She developed symptoms on 1 March and was hospitalized on 7 March.

    She was in a critical condition under artificial ventilation and died on 11 March.

    Investigations into the source of infection indicate that the case had exposure to sick poultry suspected to have avian influenza.
    (hat tip Avian Flu Diary)
  9. 0
    bangladesh again

    http://afludiary.blogspot.com/2011/0...se-in-two.html

    another toddler infected! even though both of these cases have been mild (just like all the reports of toddlers in egypt), this is not good news. mike coston's commentary over at avian flu diary explains why.

    Quote from afludiary.blogspot.com
    mild cases of h5n1 are viewed – a bit counter-intuitively – as being particularly notable because the less ill a person becomes, the more likely they are to have contact with others and potentially spread the virus.

    some scientists also worry that a decrease in severity could signal a better adaptation to human physiology.

    you may recall that concerns were expressed back in 2009 when a number of similarly aged children in egypt came down with very mild h5n1 infections.

    the institute of epidemiology disease control and research (iedcr) discovered the fresh case while mopping up the area on wednesday. it launched a drive in the locality following the detection of first case of the year in the area on sunday.

    iedcr director prof mahmudur rahman told bdnews24.com that a 31-month-old boy had been detected carrying the virus in their lab.
  10. 0
    Fukushima, Japan

    http://www.recombinomics.com/News/03...Fukushima.html

    Apparently, it's not just the tsunami, earthquake and radiation that are a big problems in this part of Japan lately. Of course, this problem lies under the radar given the scale of disaster going on over there right now.

    Quote from www.recombinomics.com
    Hokkaido University released the H5N1 sequence from a duck in Fukushima, A/duck/Fukushima/2/2011, which was collected in January, 2011. Like the sequence from the whooper swan in Hokkaido, A/whooper swan/Hokkaido/4/2011, it had S227R (in addition to V223I and M230I). A third sequence from Tochigi, A/peregrine falcon/Tochigi/15/2011, had the earlier changes (V223I and M230I), but did not have S227R.

    The duck sequence was closely related to the whooper swan protein sequence (the duck also had E362D), raising concerns that the receptor binding domain changes (V223I, S227R, M230I) are widespread in H5N1 clade 2.3.2 in northern Japan, including the region most affected by the earthquake and tsunami.

    The three receptor binding domain changes raise concerns that this emerging sub-clade could infect humans. These concerns were increased by the recent reports of two confirmed H5N1 cases in the Kamalapur area of Dhaka, Bangladesh.


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