Leucovorin Leucovorin | allnurses

LEGAL NOTICE TO THE FOLLOWING ALLNURSES SUBSCRIBERS: Pixie.RN, JustBeachyNurse, monkeyhq, duskyjewel, and LadyFree28. An Order has been issued by the United States District Court for the District of Minnesota that affects you in the case EAST COAST TEST PREP LLC v. ALLNURSES.COM, INC. Click here for more information


  1. 0 After methotrexate chemo is given, Leucovorin is ordered as a rescue drug. At the hospital I work at, the continous IVF given is a Sodium Bicarb in D5W. Our Pharmacy mixes the the IVF and Leucovorin. Leucovorin is often given in a syringe and sometimes in a 100NS bag. There is no consistency, but I know we are suppose to have it administered for about 5-15 minutes in NS. I just looked up Leucovorin in my drug book and Leucovorin is not compatible with Sodium Bicarb which I know, but as far as giving it in the syringe or IVPB in 100NS how do you guys normally do it? I feel safer giving it in the IVBP cuz sometimes I dont have the time to stand there for 5 minutes to give the push.

    From Davis Drug Guide: [HTML]http://www.drugguide.com/ddo/ub/view/Davis-Drug-Guide/51439/11/leucovorin_calcium[/HTML]

    * Concentration:
    reconstitute 50-mg, 100-mg, and 200-mg vials to a concentration of 10 mg/mL; reconstitute 350-mg vial to a concentration of 20 mg/mL
    * Rate:
    Administer by slow injection over a minimum of 3 min; not to exceed 160 mg/min
  2. 3 Comments

  3. Visit  SiennaGreen profile page
    #1 0
    I have only seen it come in a IVPB at our hospital. I can't remember but I think it comes 50mL and goes in over 15 minutes? Scheduled Q6 usually. We do Q6 urine PH also during that time. I would be wigged out pushing it....
  4. Visit  caroladybelle profile page
    #2 0
    I have always given it as an IVPB or as PO. Thankfully, my pts generally have a double lumen Hickman or PICC.
  5. Visit  mzjennx profile page
    #3 0
    Sorry late response. So I have been getting in from pharmacy as a push. But I usually don't feel comfortable so I will put it in 50 ml NS and run it for 15 mins. I guess in just figuring out what is best practice.