Maternal Vancomycin

  1. 0
    Hey NICU peeps, just wondering something...
    A mom asked me not too long ago (she was receiving IV Vanc) if the Vanc would have any effect on her baby's hearing after she delivered. I looked for the answer to her question myself and what I found suggested that there wasn't any long-term effect on hearing but some short-term hearing loss was found on a limited basis.

    I'm wondering if you guys have seen any issues in moms that have gotten Vanc. I know we give Gent all the time in our nursery (both well-baby and NICU) and while no one gets a hearing test while receiving it, presumably for that reason, I haven't heard anyone saying it's associated with long-term hearing loss down the road, at least not in the dosages and 48hr cours we use. I guess my question isn't so much about Gent but Vanc. What, if anything, have you seen?
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  3. 4 Comments so far...

  4. 1
    How is vanco administered to adults? Over what time frame, I mean? We give it over an hour to our neonates, specifically to mitigate the ototoxicity. I'd reckon if similar administration is the norm with pregnant women, the risk would be minimal.
    Elvish likes this.
  5. 0
    This particular lady was getting hers over 1.25-2 hours, depending on her dose (which of course depended on her levels). She had been on it multiple times and ID was at that point considering putting her on it for a couple weeks.

    Interesting input.
  6. 0
    Infectious Diseases in Critical Care - Jordi Rello, Marin Kollef - Google Books

    This is what I found. I know that our ID tries not to use it on pregnant women unless they absolutely have to.
  7. 0
    I haven't seen it used a whole lot either - this was the first time, actually, but this pt had active MRSA in recurring genital abscesses that were not responding to ANYthing else. Interesting info.


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