During a code blue when administering drugs Epinephrine, Atropine and Lido Cain via endotracheal tube when absence of IV access ,Why we should dilute the dose in 5cc to 10cc of normal saline? is it to promote bronchial absorption , and does large amount 10cc of normal saline can cause any harm to patient trachea ?....., Please let me know . THANKS:roll
Oct 8, '02
The dose is first doubled and diluted to a total of 10ml. Doubling the dose helps to increase the effective amount absorbed, since the lungs don't absorb all of the drug very well.
Some think that you can double an epi dose by giving 20cc of drug down the tube (2 x 10cc of 10:000), but that is a lot of fluid for the lungs to absorb (even the 10cc amount can be a bit of a challenge).
So how does one manage to get twice the amount in 10cc? You have to use multi-dose vials of the drug (higher concentration) and dilute with saline to 10cc (total). Sounds good in ACLS class, but I've yet to really see it work efficiently or effectively in or out of the hospital. Not to say it doesn't, but I wouldn't put much faith in the endotracheal route, especially if the pt is/was in CHF or has aspirated and already has fluid filled airways.
Oct 22, '02
Narcan can also be administered via ET tube.
Nov 3, '02
One thing that helps me remember is:
Drugs can go down the L.A.N.E.
10cc does seem like a lots, but I was told that with normal or elevated body temp with CPR 10cc is aerosoled pretty quickly and doesnt add to pulmonary distress.
Hope that helps!~