My father has a picc line, and a nurse to draw blood weekly, get antibioic invanz daily, and vancomycin every 48 hours. Today, she drew the blood, hooked up the invanz, and after invanz hooked up the vancomycin. She taught us(and from past picc line experieces) how to remove the tubing when its done, and how to flush. However, 30 minutes into the Vancomycin, there is blood coming out of the picc line, like it wants to go into the iv bag, almost 12 inches of blood can be seen in the tubing. Eventually the flow of the antibiotic pushes it back through the picc line, but I was wondering, is this normal? This also happened last week.