dosage problem

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My sister is required to take dosage tests at work periodically. So she passed a few of them on to me. I will post them and let me know how you figured them out, these are a little different then what I had in class.

Dobutamine ordered for 206lb male at 10mcg/kg/min

Physican wishes to double concentrate the dobutamine which means the pharmacy will send Dobutamine as 1G/250mlD5W What is the mcg/min and the ml/hr

Aren't these just too much fun ;)

OK, here we go:

If the patient weights 206 lbs, then you divide that by 2.2 to get to kilograms.

That gives you 93.64 Kg.

Multiply that by 10 to get the mcg/min

which is 936.36 mcg/min

divide 936.36 by 1000, then by 1000 again to get it to grams

which is .0009364 grams.

If there is 1 gram in 250ml, and you want .0009364 gm you cross multiply and find that .0009364 is equal to 0.23409 ml of the IV solution. since there are 60 minutes in an hour, you have to multiply that number times 60.

I got 14.5 ml per hour for the rate

and 936.36 mcg/min

Did i get anywhere close?

This is what I got.

1. lb to kg 2.2lb : 1kg=206 : X

X=93.63kg

2. 10mcg/kg 10(93.63)=936.36mcg/min

56181.8 mcg/hr or 56.18mg/hr

3. 1g: 250D5W on hand 1g=1000mg conversion used

1000:250=56.18: X

1000X=250(56.18)

X=14.1ml/hr

936.36mcg/min

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