What does it mean and is it significant for swine flu? Don't know yet. Just watching it...
Quote from www.recombinomics.com
... just prior to the release of initial sequences by Mill Hill, the WHO put up a Ukraine update on Nov 17 stating that no significant changes had been found in the sequences from Ukraine patients, but the next day 10 HA sequences were released and D225G was found in all four fatal cases. Five other sequences from milder cases infected with the same sub-clade strongly suggested the linkage to fatal cases was significant.
The sequence data led to the examination of earlier sequences generated in several countries, including Norway. An alert was issued when Norway found 3 sequences with D225G, which were from two fatal cases and one severe case, which was the first severe cases reported in Norway.
The Norway study also found a statistically significant association of D225G and D225N with severe and fatal cases. They also found D225G on multiple genetic backbones, providing additional support by acquisition by recombination.
The Norway data, as well as sequences from Ukraine, Russia, the United States and other countries show clear clustering and decisively refute WHO claims of lack of significance as well as spontaneous appearances due to copy errors.