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Need Help with Humulin 70/30 question



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Sep 23, 2009 02:10 PM

Need Help with Humulin 70/30 question


Hi, I am a nursing student trying to gain insight into when the highest risk for a hypoglycemic episode occurs after administration of a 70/30 NPH/regular premix? I have been through as much literature as I can find and am still confused. Basically how many hours after an AM dose should I be expecting a hypoglycemic reaction to occur? Thanks so much.

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5 Comments
No. 1
from classicdame
Old Sep 25, 2009, 12:42 PM

Default Re: Need Help with Humulin 70/30 question
the one that has the fastest action is the regular insulin. It peaks in about 2 hours.
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No. 2
from TerriM67
Old Sep 26, 2009, 12:41 AM

Default Re: Need Help with Humulin 70/30 question
That was my thinking. The regular insulin peaks around 2 hours while the NPH is kicking in so I chose the answer of between 8-10 AM on my test. The correct answer was 4-6 pm and I am just not understanding why. The manufacturer's rep even stated that the mix peaks at about 2 1/2 hrs so I am feeling a bit lost.
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No. 3
from kids
Old Sep 26, 2009, 01:19 AM

Default Re: Need Help with Humulin 70/30 question
Originally Posted by TerriM67 View Post
Hi, I am a nursing student trying to gain insight into when the highest risk for a hypoglycemic episode occurs after administration of a 70/30 NPH/regular premix? I have been through as much literature as I can find and am still confused. Basically how many hours after an AM dose should I be expecting a hypoglycemic reaction to occur? Thanks so much.
I carry this table http://www.isletsofhope.com/diabetes...n_types_1.html
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No. 4
from TerriM67
Old Sep 27, 2009, 01:32 AM

Default Re: Need Help with Humulin 70/30 question
Thanks so much for your help. I love the chart!
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No. 5
from classicdame
Old Oct 02, 2009, 04:31 PM

Default Re: Need Help with Humulin 70/30 question
would have to see the whole question. One reason regular insulin is no longer favored in acute care is that the breakfast dose and the lunch dose meet around 2 p.m. and cause hypoglycemia. Regular continues to work about 8 hours, but we re-dose in about 4 for lunch. Too much on board when that second dose peaks. Plus, regular is always treating highs, not preventing them.
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