Published
The pathophysiology explains the clinical manifestations & laboratory findings. Always connect them.
For example: Pancreatitis is highly common among alcoholics. This is because the scar tissue that forms due to the alcohol eventually blocks off the ducts that would typically evacuate the pancreatic enzymes that would eventually flow into the small intestine. So these enzymes essentially get stuck in the pancreas, based off basic biology you know that enzymes break down, right? The enzymes begin to autodigest the pancreas causing extreme pain and discomfort as the primary symptom.
Another example, diabetics (typically uncontrolled diabetes or undiagnosed diabetes) will first note contact urination/thirst/eating. Otherwise known as polyuria, polydypsia, and polyphagia respectively. This is because the blood is in a hyperosmolar state (because of all the sugaaaa) and the kidneys react by diuresing. The thirst comes from the hyperosmolar state and the excessive urination.
The hunger is because none of the glucose being taken in orally is being taken in intracellularly and thus the body is still like: "omg I need energy ... feed me".
cshughes
1 Post
Need tips to keep up with diseases and manifestations for patho!