Oxygen administration - page 2
I am a nursing student and I have an evidence based research project to do. We were instructed to pick a topic/question about nursing interventions. I am having trouble finding the information I need... Read More
Sep 30, '09You're mssing the point, and obviously did not read the study. There is no singular "hypoxic drive", in other words just because a chronicly hypercapnic person's central and peripheral chemoreceptors have aclimated to raised CO2 levels, CO2 still remains the principle factor in ventilation. On rare occasion (such as your single anecdote) said person may experience further increased CO2 by other mecahnisms than hypoventilation and suffer CO2 narcotization.
Sep 30, '09I did read the article. If a patient needs O2 they are always titrated to maintain the best sats and respiratory response. If they need ventilation they get it, if they need BiPap or CPAP they get it. In no way do I advocate the withholding of O2, whether they are COPD patients or not and they need it. You have to look at the whole patient and see what they need. However, in a patient who is stable, like any medication, O2 needs to be titrated to need. Just because someone is a COPD patient does not mean they need 6 lpm O2 either. * absorption atelectasis, oxygen toxicity, and depression of ciliary and leukocyte function at FIO2 values above 0.5 has been noted. Now to address the hypoxic drive I can understand the premise of the article and I know what they are saying. All I can say is how I have seen people react to oxygen delivery and the improvement of someone's respiratory status by titrating down the O2. It may not be due to the "Hypoxic drive" per se and that's fine, but nonetheless that particular patient (and by the way I have seen it in more than one patient and we discussed it in our office and more than one therapist has seen several cases where that has happened) did not tolerate high levels of oxygen. It is something you have to watch out for no matter what the studies say. The patient woke up and their respiratory status and SaO2's improved with decreased O2. You can't just quote a report and say it never happens whether it is the "Hypoxic drive or not".