Mixing medications for emergency treatments - page 2

I've been working in psych for almost 2 years. I've been putting haldol, benadryl and ativan in the same syringe for the entire time I've been working this specialty. I remember asking about this... Read More

  1. Visit  Wabi Sabi profile page
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    At my facility, we do combine Haldol and Ativan together and give Benadryl by itself.
  2. Visit  Chaser profile page
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    According to my drug book benedryl is not syringe compatible with much. This includes haldol and ativan. Haldol and ativan however are compatible. I ussually use two seperate syringes. We call that a B52 as well. I much prefer giving zyprexa 10mg most of the time however. Works sooooo fast!
  3. Visit  anna07banana profile page
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    I am a psychiatric nurse with background in inpatient crisis stabilization and corrections. This question came up when I was asked why Haldol, Ativan, and Benadryl can't go in the same syringe.
    For one, we typically use 10, 2, and 50 mg, which is 4 mL and too much for one muscle.
    And for two, Benadryl never gets mixed with Haldol in the same syringe: precipitate forms in about 5 minutes. The pH is changed which may alter the effectiveness of one or both medications (depending on what the Benadryl is mixed with) resulting in decreased or increased effects and may cause irritation and possible damage to the injection site.
    Many times since this is given as an ETO, the cocktail does not sit out for that long, but it still precipitates whether it is in the syringe or in the muscle!
    Also, Haldol is compatible with Ativan, but not Valium. When Ativan was nationally back-ordered in the beginning of 2012, we had to order Valium to replace it. That meant there were 3 syringes being used to deliver Haldol, Valium, and Benadryl.


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