experienced manager : new facility

Is there any managers out there that may have experienced a difficult change. I am an experienced nurse manager that has relocated to a new facility that has been functioning for a good 13 years. The staff are hesitant to change, but I do not like the daily functions. I have made small changes in accordance to state and federal regs, but the problem is much greater. The area office is located on the second floor of my facility. I am in an outpatient dialysis facility. When something is done not to the satisfaction of the staff, the chain of command is one step above me.
The administrative secretary has family that is part of my staff.All of the complaints come to me from the secretary, not the staff. I was told that the staff feels that I am trying to mold them into the facility I came from. Any suggestions on how to maintain or gain the control I need ? I wanted to appear nice when I started, but now I feel I am being walked on. Help !

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