I have a patient who was admitted to the hospital today for a DVT (his 2nd) in his thigh. He has all sorts of medical issues, and should be on anticoagulant therapy for the rest of his life. But here's the catch-he is at great risk for injury due to active alcoholism and homelessness, and is frequently falling and getting beat up out on the streets. He's had some pretty serious injuries over the last few years, and I'm afraid that anticoagulating him is going to leave him vulnerable to a serious or life threatening bleed. Of course, the flip side isn't great either-he's at risk for another DVT or PE if he's not on coumadin. He'll be seeing me for followup, and I'm not sure what the best course of action is. Any thoughts or advice?