Heparin therapeutic range? Heparin therapeutic range? | allnurses

Heparin therapeutic range?

  1. 0 I'm in my final semester of nursing school and am unsure of one math problem. I've already conferred with other students and we have not reached a consensus. Hopefully someone here can enlighten us.

    You find your pt's heparin drip running at 10cc/hr. concentration is 20,000 units in 500 mL D5W. How much hep is pt getting per hour? Simple enough, 400 units/hr. Here's where the uncertainty comes in: Is this within a therapeutic range? I would think yes because 20,000 units is a typical dose, but at that rate it would take 50 hours to receive it all. Is that too long of a time to be therapeutic (book says normally administered over 24hrs)? Wouldn't it depend on the individual pt's pTT? Or do I just forget the rate and look at the dose to determine if therapeutic? Please please point my thinking in the right direction. Thanks!
  2. 3 Comments

  3. Visit  NanSeeH profile page
    #1 0
    You are correct in thinking that your answer depends on the individual patients pTT. You would have a lab value to tell you if the patient is within the therapeutic range, if not then there will be an algorhythm for lowing or increase the drip rate (# units)

    Hope this helps
  4. Visit  zacarias profile page
    #2 0
    Just like above, the the aPTT will show if it is therapeutic. Heparin doses vary...for instance a large 350 lbs man may require a much larger dose than someone else to be therapeutic but again we look at the aPTT (or HEPACT in my hospital) to find out if it's therapeutic.
  5. Visit  Spatialized profile page
    #3 0
    I agree with everyone above that there should be a aPTT drawn to match with the protocol, but I had just written up heparin for class and came across this tidbit (which may or may not be helpful); with regards to continuous drips, the rate runs 10-18 units/kg/hr. Of course if you don't have a weight, this is a moot point. At least you could ask you prof. about it in this light...