Allergic reaction to sulfa antibiotics

Nurses General Nursing

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Pharm class got me thinking ...

A long time ago when I was 20 I was referred to a urologist for tx of recurring UTIs. She prescribed an antibiotic (which one is a mystery - I didn't pay much attention at the time :stone ). Approx. 6 hours after I took the first dose I began feeling nauseated. I dozed for a while, then woke up with severe shaking chills. This continued throughout the night - I thought I was going to die. When I finally crawled out of bed the next morning and looked at myself in the bathroom mirror, my skin had turned bright red. You would have thought I was sunburned. No rash or blotchiness, just bright red. I called the doctor, who said, "you're having a reaction to the drug - stop taking it. And don't ever take any other sulfa drug." The redness took about another 24 hours to subside.

Have any of your ever seen/heard of a reaction like this to sulfa or other antibiotics? (or am I the only lucky one :rolleyes: ) Could this have been a form of Stevens-Johnson syndrome?

Just trying to learn more about this ... thanks for your help!

my dtr. used to take bactrim for her ear infections until one time she had a sandpaper rash covering her abdomen. her pediatrician labeled it an allergy. now is it true that people that are allergic to sulfa, cannot take lasix?

When I was 15, I was prescribed sulfa for an UTI - I have a hx of anaphylaxis with penicillin. Within 2 hours of taking the sulfa I developed muscle twitches, chills and mild cyanosis. My mom nearly had a cow as she remembered my reaction to pcn when I was a toddler.

I have never heard of a problem with lasix but have heard that people w/ pcn allergy can be hypersenstive to cephalosporin and sulfa meds. I am very cautious about antibiotics I am prescribed - some docs are great and others are just plain careless.

my dtr. used to take bactrim for her ear infections until one time she had a sandpaper rash covering her abdomen. her pediatrician labeled it an allergy. now is it true that people that are allergic to sulfa, cannot take lasix?

People who are allergic to sulfa can have a sensitivity to any of the sulfa-based drugs, including Lasix. I found out the hard way that Celebrex (NSAID) has sulfonamides in it. I am allergic to sulfa and when I took a sample dose of Celebrex that the doctor had given me, I developed hives and a swollen face. If you go to Google and type in "lasix sulfa allergy", there are all kinds of links to articles that explain the cross-sensitivity.

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